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The setting is the year 202X, in Kamata, Ota Ward, Tokyo. This area has transformed into one of the world's premier entertainment hubs following the opening of the Kamata Line. The district draws significant economic advantages and is rife with organized crime, foreign mafias, terrorists, smugglers, prostitution rings, and the covert schemes of political, financial, and governmental power brokers.
A newly assigned police officer, Nonogami, stationed at the front police box near the station, feels overwhelmed by the pervasive corruption. However, with the formidable presence and overwhelming force of Tyranno, a towering female police officer, the cases start getting resolved.

