Farabeuf said:
Calm before the storm chapter it seems to me. The ominous, foreboding "she may not want the sa,e as you" warning is repeated here. I very much fear that a recovered Casca might have her memories reset to a pre Guts time, and as such, be all in on joining Griffith in Falconia. That would drive Guts insane.
That would be waaaayy too much of an anti-climax, and an illogical one too in several ways. Fans have waited so many years for a Guts-Casca reunion that I don’t think it would end any other way than in them eventually embracing each other.
Skull-Knight’s words are most likely referring to Casca possibly wanting to stay insane rather than live sane with memories of the Eclipse.