Fuck, just like the anime, this makes me cry.
I didn't expect to cry again after already have experienced it from (three in total with the original FMA included) rewatching the anime of that scene a few days ago.
Knowing what happens since first watching it in 2009.
It hurts even more seeing the moment we first see Nina/Alexander as a Chimera.
Everytime Nina speaks, it breaks my heart. Worse before her death in the manga. In the anime, I sobbed in the beginning as well, but moreso at the moment she speaks to Edward and then Al.
The anime expanded this scene greatly, but the simplicity of the single words from Nina in the manga hits different in a more depressing way over the lines of the English Dub.
Nonetheless, the scene remains great in whatever form.
Rewatching the first anime's version, it's the lesser one, arguably mediocre in comparison, but still a sad scene.
That damn Shou Tucker is a sick piece of shit bastard for turning his wife and daughter into Chimera's.
Easily one of the best saddest scenes in anime. Next to the likes of Clannad After Story which makes me sob the most.