Misao is a fairly skilled ninja from the Oniwabanshū clan of onmitsu, previously based in Edo. Her weapon of choice is the kunai. Misao is around sixteen years old when she is first introduced, though she appears younger.
Misao is the granddaughter of the former okashira of the Oniwabanshū. She was initially under the care of the last leader of the Oniwabanshū, Shinomori Aoshi. However, when Misao was eight, Aoshi, along with Han'nya, Shikijō, Beshimi, and Hyottoko, left her in the care of Kashiwazaki Nenji, also known as Okina of the Oniwabanshū. Despite this, Misao shared a strong bond with Okina, but in her mind, Aoshi remained the best. She had a special affection for Han'nya, who always took care of her and taught her how to fight.
When Misao heard that Aoshi was in Tokyo, she decided to search for him. On her way back to Kyoto, she encounters Himura Kenshin. This meeting sets the stage for further adventures and connections in her journey.
