Mariko successfully brought Lucy to the afterlife along with her thanks to the explosion permanently regressing into the Nyu persona and it looks like Nana and Nyu's finally going to get the slice of life treatment they've always longed for at least until that damned director finds them.
It's too bad that Kurama took his own life but I guess that it'd be the end of him either way since he crossed his superior for the very last time.